منابع مشابه
Transcription keeps it simple
new report shows that a eukaryotic transcription factor is directly activated by a metabolite of the pathway it controls. Although this idea has been proposed for several regulatory systems, Christopher Sellick and Richard Reece (University of Manchester, UK) are the first to demonstrate direct binding to and activation of a eukaryotic transcription factor by a small molecule metabolite. The in...
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It is believed that the length of a person’s life depends on a mixture of economic and social factors. Yet the relative importance of these is still debated. We provide evidence in this paper that marriage has a much more important (positive) effect on longevity than high income does. For men, it almost exactly offsets the large negative effect of smoking. Economics, however, plays little or no...
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The liver in general and hepatocytes in particular maintain an awesome array of function—synthesis, catabolism, intermediary metabolism, and detoxification. Recent work has enlarged our knowledge of the factors that permit this range of function to be expressed, and in particular the complex inter-relations of cellular and non-cellular elements in the liver that contribute to this. The function...
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In our paper we discuss the existence of narcissism as instinct; a Mendelian trait that can be inherited from either parent. This instinct is an essential component of five different personalities in our model and these personalities can be classified into two groups: Narcissistic and Obsessive. How these personalities manifest in individuals and how the individual interacts with the healthcare...
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ژورنال
عنوان ژورنال: Nature Reviews Molecular Cell Biology
سال: 2009
ISSN: 1471-0072,1471-0080
DOI: 10.1038/nrm2638